The Turtles take to the sewers to confront the deadly new creature that has been stalking mutants. When their home court advantage is turned against them, no one is safe! Meanwhile, a falling out between Baxter and April could have dire consequences for Mutant Town!

The war is over. The Dragon is destroyed. The city is saved. But at what cost? Splinter is gone, the Turtles are in disarray, and the Shredder has returned. But all is not as it seems as the Turtles' most-feared enemy struggles with this new opportunity to regain his honor. Meanwhile, a nearly decimated Foot Clan belongs to Karai, but can she truly rise to the task in the shadow of its greatest warrior? And how does a newly-changed Leatherhead fit into a post-mutation NYC?